| 01 | Biomedicine & Health· Major MemBrain v2: an end-to-end tool for the analysis of membranes in cryo-electron tomographyE 88I 90N 72 | 76 | 88 | 90 | 72 | Firming up | Sep 8, 2026 |
| 02 | Biomedicine & Health· Notable Comparative analysis of mitochondrial proteomes across the tree of lifeE 92I 50N 76 | 73 | 92 | 50 | 76 | Early signal | Oct 1, 2026 |
| 03 | Biomedicine & Health· Notable Cohesin prevents local mixing of condensed euchromatic domains in living human cellsE 91I 55N 81 | 73 | 91 | 55 | 81 | Early signal | Sep 1, 2026 |
| 04 | AI & Computing· Notable Tangermeme: a toolkit for understanding cis-regulatory logic using deep learning modelsE 85I 67N 69 | 72 | 85 | 67 | 69 | Early signal | Oct 8, 2026 |
| 05 | Biomedicine & Health· Notable Mitochondrial proteome of Acanthamoeba delineates aerobic and anaerobic pathways dynamically regulated by oxygenE 94I 46N 75 | 72 | 94 | 46 | 75 | Early signal | Oct 1, 2026 |
| 06 | Neuroscience· Notable A population code for semantics in human hippocampusE 88I 56N 75 | 72 | 88 | 56 | 75 | Early signal | Sep 30, 2026 |
| 07 | AI & Computing· Notable Reimagining research papers as interactive and reliable AI agentsE 94I 54N 75 | 72 | 94 | 54 | 75 | Early signal | Sep 16, 2026 |
| 08 | Neuroscience· Notable What one sees depends on how far the eye has movedE 89I 41N 90 | 72 | 89 | 41 | 90 | Early signal | Aug 30, 2026 |
| 09 | Biomedicine & Health· Notable A DNA Typewriter records the cell lineage history of a mouse, from zygote to late organogenesisE 93I 44N 74 | 71 | 93 | 44 | 74 | Early signal | Oct 8, 2026 |
| 10 | AI & Computing· Notable Decoding systemic vascular health and hypertensive disorders in pregnancy through retinal imaging and Visionary AIE 86I 41N 80 | 71 | 86 | 41 | 80 | Early signal | Oct 6, 2026 |
| 11 | Climate & Environment· Notable Agricultural liming is a carbon sink in the Mississippi River BasinE 94I 44N 78 | 71 | 94 | 44 | 78 | Early signal | Sep 23, 2026 |
| 12 | Biomedicine & Health· Notable A Virtual Cell Model That Predicts How Cells React to Being PerturbedArc Institute's State transformer forecasts gene-expression responses in cell types it never trained on. E 94I 70N 69 | 71 | 94 | 70 | 69 | Early signal | Aug 31, 2026 |
| 13 | Biomedicine & Health· Notable Prehistoric global migration of vanishing gut microbes with humansE 89I 36N 77 | 70 | 89 | 36 | 77 | Early signal | Oct 7, 2026 |
| 14 | Materials & Energy· Notable X-ray liquidography decodes complex motions in azobenzene isomerizationE 94I 40N 77 | 70 | 94 | 40 | 77 | Early signal | Sep 30, 2026 |
| 15 | Neuroscience· Notable Lifespan single-cell transcriptomic atlas of the human prefrontal cortexE 96I 44N 75 | 70 | 96 | 44 | 75 | Early signal | Sep 23, 2026 |
| 16 | Biomedicine & Health· Notable In mice, a population of male germ cells show characteristics of nonapoptotic cell death during G0 arrestE 86I 40N 76 | 69 | 86 | 40 | 76 | Early signal | Oct 12, 2026 |
| 17 | Neuroscience· Notable Single-cell atlas of transcriptomic vulnerability across brain disordersE 96I 48N 70 | 69 | 96 | 48 | 70 | Early signal | Sep 23, 2026 |
| 18 | Physics· Notable Gravitational torque drives multidecadal variations in length of dayE 94I 44N 73 | 69 | 94 | 44 | 73 | Early signal | Sep 23, 2026 |
| 19 | Biomedicine & Health· Notable Intermittent or Continuous Renal-Replacement Therapy in Acute Kidney InjuryE 76I 51N 73 | 68 | 76 | 51 | 73 | Early signal | Oct 14, 2026 |
| 20 | Neuroscience· Notable Shedding light on left hippocampal mGlu5 in Alzheimer’s diseaseE 88I 39N 73 | 68 | 88 | 39 | 73 | Early signal | Oct 12, 2026 |
| 21 | Physics· Notable A thorium-229 optical nuclear clock with feedback loopE 91I 49N 66 | 68 | 91 | 49 | 66 | Early signal | Oct 7, 2026 |
| 22 | Physics· Notable A nuclear clock synchronized to 229ThE 91I 50N 67 | 68 | 91 | 50 | 67 | Early signal | Oct 7, 2026 |
| 23 | Climate & Environment· Notable Deep learning of fossil pollen morphology reveals 25,000 y of ecological change in eastern African grasslandsE 89I 41N 74 | 68 | 89 | 41 | 74 | Early signal | Oct 2, 2026 |
| 24 | Biomedicine & Health· Notable Acanthamoeba ATP synthase structure reveals the TCA cycle is tethered to OXPHOSE 94I 44N 69 | 68 | 94 | 44 | 69 | Early signal | Oct 1, 2026 |
| 25 | Neuroscience· Notable Prion-like transmission of human tau strains in the mouse brainE 93I 55N 64 | 68 | 93 | 55 | 64 | Early signal | Sep 30, 2026 |
| 26 | Biomedicine & Health· Notable A transcription factor regulates development of a bacteria-housing eukaryotic cell through DNA damage mitigationE 91I 34N 77 | 68 | 91 | 34 | 77 | Early signal | Sep 24, 2026 |
| 27 | Neuroscience· Notable The lipidomic architecture of the mouse brainE 94I 51N 68 | 68 | 94 | 51 | 68 | Early signal | Sep 23, 2026 |
| 28 | Neuroscience· Notable Ultrafast venous and sagittal sinus constrictions in the brain driven by abdominal pressureE 93I 44N 73 | 68 | 93 | 44 | 73 | Early signal | Sep 23, 2026 |
| 29 | Biomedicine & Health· Notable Efficient differential expression analysis of large-scale single-cell transcriptomics data using DreamletE 89I 63N 64 | 68 | 89 | 63 | 64 | Early signal | Sep 23, 2026 |
| 30 | Biomedicine & Health· Notable Molecular-level observation of the self-assembly of a virus-like particleE 94I 46N 72 | 68 | 94 | 46 | 72 | Early signal | Sep 16, 2026 |
| 31 | Physics· Notable Discovery of an intrinsic non-Hermitian phase transition in a bulk condensed-matter systemE 94I 45N 73 | 68 | 94 | 45 | 73 | Early signal | Sep 10, 2026 |
| 32 | Space & Astronomy· Notable A spatial map of the atmospheric limb of a hot JupiterE 85I 49N 67 | 67 | 85 | 49 | 67 | Early signal | Oct 14, 2026 |
| 33 | Biomedicine & Health· Notable The genetic basis for the production of toxic quinolizidine alkaloids in lupinsE 78I 43N 74 | 67 | 78 | 43 | 74 | Early signal | Oct 8, 2026 |
| 34 | Space & Astronomy· Notable Incorporation of atmospheric components in planetary magma oceans through bubble–metal compoundsE 92I 38N 72 | 67 | 92 | 38 | 72 | Early signal | Oct 1, 2026 |
| 35 | Biomedicine & Health· Notable Comprehensive lineage tracing maps the landscape of cell fate decisions in mouse embryogenesisE 89I 41N 71 | 67 | 89 | 41 | 71 | Early signal | Oct 1, 2026 |
| 36 | Neuroscience· Notable Intrinsic rewards guide visual resource allocation via reinforcement learningE 86I 45N 70 | 67 | 86 | 45 | 70 | Early signal | Oct 1, 2026 |
| 37 | Biomedicine & Health· Notable A high-confidence plant mitochondrial proteome via protein correlation profilingE 92I 44N 69 | 67 | 92 | 44 | 69 | Early signal | Oct 1, 2026 |
| 38 | Biomedicine & Health· Notable Repeated marine-to-freshwater fish transitions reveal paleoenvironmental modulation of adaptive radiationE 88I 51N 67 | 67 | 88 | 51 | 67 | Early signal | Sep 30, 2026 |
| 39 | Biomedicine & Health· Notable Butterfly wing patterns in flight create powerful illusory motion cuesE 94I 37N 70 | 67 | 94 | 37 | 70 | Early signal | Sep 30, 2026 |
| 40 | Materials & Energy· Notable Phototropic and skototropic growth in inorganic filmsE 91I 33N 75 | 67 | 91 | 33 | 75 | Early signal | Sep 28, 2026 |
| 41 | Other frontiers· Notable Continuous UV irradiation played an inconclusive role in selecting the canonical genetic alphabetE 89I 37N 74 | 67 | 89 | 37 | 74 | Early signal | Sep 28, 2026 |
| 42 | Neuroscience· Notable Single-nucleus transcriptome-wide association study of human brain disordersE 96I 48N 67 | 67 | 96 | 48 | 67 | Early signal | Sep 23, 2026 |
| 43 | Biomedicine & Health· Notable Developmental xenocortication using human-derived organoids in miceE 94I 48N 69 | 67 | 94 | 48 | 69 | Early signal | Sep 16, 2026 |
| 44 | AI & Computing· Major Accelerating scientific discovery with Co-ScientistA multi-agent AI system on Gemini that generates and validates scientific hypotheses E 94I 88N 72 | 67 | 94 | 88 | 72 | Firming up | May 19, 2026 |
| 45 | Space & Astronomy· Notable Two families of multi-planet systems with distinct architectures and stellar hostsE 85I 48N 65 | 66 | 85 | 48 | 65 | Early signal | Oct 13, 2026 |
| 46 | Neuroscience· Notable Heterochronicity shapes brain network formationE 86I 39N 70 | 66 | 86 | 39 | 70 | Early signal | Oct 12, 2026 |
| 47 | AI & Computing· Notable Large language models unlock the ecology of species interactionsE 85I 56N 64 | 66 | 85 | 56 | 64 | Early signal | Oct 8, 2026 |
| 48 | Space & Astronomy· Notable Discovery of a second-generation planet candidate accreting onto a white dwarfE 90I 40N 68 | 66 | 90 | 40 | 68 | Early signal | Oct 5, 2026 |
| 49 | AI & Computing· Notable Scalable decision-making for games of imperfect informationE 94I 39N 68 | 66 | 94 | 39 | 68 | Early signal | Sep 30, 2026 |
| 50 | Biomedicine & Health· Notable Barrier immune memory is programmed by intestinal epithelial cell presentation of cytosol-delivered bacterial antigensE 91I 38N 70 | 66 | 91 | 38 | 70 | Early signal | Sep 30, 2026 |
